Nov'25·Jordi Capdevila·5 MIN

How is Neuroscience Transforming the Digital Advertising Landscape

Home How is Neuroscience Transforming the Digital Advertising Landscape

The digital advertising landscape is at a crossroads. After years of optimizing for impressions, reach, and automation, the industry has drifted away from what matters most: human connection and understanding what drives people's motivations in the moments that matter most. An ad may have high visibility, yet fail to ignite the emotional or cognitive connection required to move someone to act.

This raises a critical question: What is the current digital advertising landscape really optimizing for, performance metrics or human relevance?

Our new research, developed in partnership with Prof. Moran Cerf, a leading neuroscientist at Columbia University, provides scientific evidence that the brain naturally prefers information that feels intuitive, emotionally aligned, and easy to process. When advertising aligns with the moment someone is in, how they think, feel, and intend to act, the ad resonates more naturally and becomes far more impactful.

This is the foundation of neuro-contextual advertising, a more human-centered approach that enables brands to build genuine connections in real-time

 

 

  1. The Limits of Behavioral Targeting
  2. First Things First: What Is Contextual Advertising?
  3. Introducing the Neuro-Contextual Advertising Approach
  4. The Brain Sets the Standard for Real Relevance
  5. A Human-Centered Future Built on Neuro-Contextual Understanding

 


Key Takeaways: Digital Advetising Landscape

  • Advertising focuses too heavily on automation and KPIs that don’t reflect real human impact, losing sight of the emotional and cognitive connection.
  • Behavioral targeting is declining in accuracy and scale, capturing past behavior instead of present intent.
  • The brain prefers information that feels intuitive, emotionally aligned, and easy to process, making people more receptive to advertising.
  • Neuro-contextual advertising interprets the context of an article or video to decode deeper user signals of interest, emotion, and intent to match the cognitive and emotional state of the moment.
  • Liz, our proprietary neuro-contextual AI, enables privacy-first, human-centered relevance, without using personal data.


The Limits of Behavioral Targeting

For more than a decade, behavioral targeting promised precision by tracking where people went and what they did online. What it captured were digital traces, not genuine human understanding. It relied on demographics and past behavior, placing people into fixed categories that did not reflect the real motivations or emotional context shaping their decisions.

It is not a small disruption. It is a structural failure that has revealed long-standing gaps in how audiences are understood, which has drained budgets and weakened performance across the funnel.

At the same time, people have changed. Loyalty is declining, attention is fragmented, and users are increasingly uncomfortable with the idea of their personal data being used without their permission. Decisions are shaped by emotional context rather than broad demographic labels. Someone’s age or gender cannot explain why they are searching, what motivates them, or how they're likely feeling in the moment an ad appears.

Neuroscience has validated what the industry is only now rediscovering. Human readiness is contextual. Emotion is what first signals relevance and opens the door. Interest is what draws attention and keeps someone engaged. Intention transforms that engagement into action, whether it’s a conversion or a purchase.

Our study reveals that these signals come from the content people are actively engaging with. Emotional tone, cognitive state, and intent expressed in the surrounding environment influence how the brain receives an ad. These patterns appear in the EEG brainwave technology results through stronger attention, emotional resonance, and neural engagement when ads align with the mindset activated by the content.

To connect in a privacy-first world, advertisers need to understand the moment itself. Our research shows that alignment with interest, emotion, and intent present in the content strongly impacts people's receptiveness to ads. These signals come from the context of the moment, not from personal identifiers or historical tracking.

In this sense, context is not a fallback. It is simply where the study recorded the strongest neural and emotional responses. When advertising matches the mindset a person is already in, the brain processes the message more fluently. This is the foundation of Neuro-Contextual advertising and the relevance observed in the research.

 

1 How is Neuroscience Transforming the Digital Advertising Landscape

First Things First: What Is Contextual Advertising?

As behavioral data declines, many marketers are revisiting contextual advertising and rethinking how they can create relevance without personal data. This shift has renewed a long-running debate between behavioral and contextual approaches. Behavioral data looks backward, capturing what someone once did, while contextual aims to understand the environment a person is in right now. To understand why the landscape needed to evolve, it is helpful to start with a simple question: What is contextual advertising?

In practical terms, standard contextual targeting places ads based on page topics, usually identified through keywords or broad IAB categories. While this approach is privacy-safe, it often lacks the nuance needed to capture real human intent. Contextual systems may classify content correctly but still miss the motivation behind it. For example, a wellness retreat ad might appear on a fitness site simply because both are tagged as “health.” The match is technically correct, yet contextually off, because they do not share the same intent or emotional state.

This limitation becomes even more apparent as consumer behavior grows more fluid and emotionally driven. Traditional contextual targeting can recognize what someone is reading, but not why they are there, how they are likely feeling, or what they may be preparing to do after reading that content. 

This is exactly where standard contextual advertising reaches its limit and where neuro-contextual advertising begins to set a new standard for human relevance.

 

Introducing the Neuro-Contextual Advertising Approach

Neuro-contextual advertising represents the next evolution of contextual advertising. Built at the intersection of neuroscience and artificial intelligence, it interprets deeper signals of interest, emotion, and intent from the content people are reading or watching 

At the heart of this approach is Liz, our proprietary neuro-contextual AI. Liz mirrors the sophistication of human thought by interpreting these deeper signals in real time and delivering privacy-first,full-funnel advertising across premium CTV, video, and the open web.

The evidence is clear: the report confirmed that aligning ads to these cognitive and emotional signals produces significantly stronger effects:

  • 3.5x higher neural engagement than non-contextual ads.
  • 26% stronger emotional response than standard contextual ads.

Stronger neural responses indicate a higher likelihood of recall and downstream impact, meaning ads are not only noticed but also remembered and acted on.

Using EEG brainwave technology, the main outcomes demonstrate that neuro-contextual ads generate higher shared neural response, deeper emotional resonance, and stronger attention

Neuro-Contextual Advertising is a part of the experience rather than an interruption.

 

2 How is Neuroscience Transforming the Digital Advertising Landscape

The Brain Sets the Standard for Real Relevance

Our neuroscience study explains that the brain instinctively prefers information that feels intuitive, emotionally aligned, and easy to process. This comes from our reliance on fast, automatic thinking to navigate daily decisions.

Three core signals shape how people respond to content:

  • Emotion — signals immediate relevance
  • Interest — sustains attention
  • Intention — drives action

Together, they form the natural sequence that underpins effective advertising. When the environment aligns with the right emotional and cognitive tone, people become more open, more engaged, and more likely to connect with the message.

A Human-Centered Future Built on Neuro-Contextual Understanding

The research makes one insight clear: people process content emotionally, not only semantically. The emotional tone of the environment shapes how someone feels about the message they see, and how likely they are to remember it.

Neuro-contextual advertising is designed for this reality. It interprets why someone is consuming content and how the surrounding environment shapes their emotional and cognitive state. Neuro-Contextual AI, powered by embedding technology, analyzes the context of a piece of content to decode deeper user signals of interest, emotion, and intent in real time. It moves beyond simple content classification to create a more human-like understanding of how people think, feel, and decide.

This deeper alignment reduces cognitive effort, increases attention, and strengthens connection. 

Download the full study to explore the scientific framework behind neuro-contextual advertising and learn how brands can build deeper relevance across today’s digital environments.

 

 

Neuro-contextual Research PR image

 

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