Dec'25·Shari Munoz·4 MIN
How Neuromarketing Is Redefining Ad Relevance Today
Interested to find out more about how our contextual advertising can help you boost your brand?
For Advertisers For PublishersGet the latest news about Contextual Advertising right into your inbox!
Digital advertising is entering a period of transformation. After years of optimizing for automation, reach, and performance metrics, the industry faces a challenging limitation. Efficient delivery does not guarantee meaningful engagement, and the signals that once guided traditional marketing and targeting are fading because of changes in consumer behavior and privacy regulations.
Our new neuroscience research, conducted with Prof. Moran Cerf of Columbia University, shows that the way people respond to advertising is shaped by the emotional and cognitive state activated by the content they consume in the moment. The results demonstrate that when an ad appears in an environment that aligns with a person’s interest, emotional tone, and intent, the brain produces stronger attention, emotional response, and neural activity.
Neuromarketing, also known as consumer neuroscience, offers a deeper understanding of these reactions. As a discipline, it uses neuromarketing techniques such as eye tracking, heart rate monitoring, pupil dilation, facial coding, brain scans, functional magnetic resonance imaging, and electroencephalogram (EEG) to measure brain activity to observe emotional reaction and attention. These methods reveal signals that traditional market research or focus groups cannot capture because they measure reactions that occur before conscious awareness.
Even with this strength, traditional neuromarketing usually examines the ad in isolation. It asks how a person responds to a specific creative asset. What it does not fully examine is the environment that shapes the emotional and cognitive state a person brings into the moment. People switch between devices, topics, and formats throughout the day. Their intentions, motivations, and emotions shift as they engage with different types of content. The moment before the ad appears plays a major role in determining how the brain receives it.
Using EEG brainwave technology, our neuroscience study measured how people responded to ads placed within different types of content environments. Participants viewed non-contextual ads, standard IAB contextual ads, and Neuro-Contextual ads while neural responses were recorded.
Our research found that Neuro-Contextual Advertising generates significantly stronger neural responses when it aligns with the interest, emotion, and intent expressed in the surrounding content. This insight reflects a core principle of neuromarketing and supports the neuromarketing definition that emphasizes how emotional engagement and attention shape consumer decisions.
Neuro-Contextual Advertising builds on this foundation. Neuromarketing explains how the brain reacts, while Neuro-Contextual Advertising identifies where those reactions can be amplified. It connects neuroscience with the role of AI to interpret the meaning of the content people choose to engage with. This includes the emotional tone, cognitive load, and motivational state reflected in that content. These insights support media planning decisions that reveal how people naturally think and feel.
- A New Perspective on Neuromarketing
- How Neuro-Contextual Advertising Works
- Deep dive into the Research
- What Brands Can Learn From the Study
Neuromarketing Highlights
- Advertising becomes more effective when it aligns with the interest, emotional tone, and intent expressed in the surrounding content.
- Neuro-Contextual Ads produce significantly stronger neural engagement, reaching up to 3.5x higher than non-contextual ads.
- Neuro-contextual ads offer 26% stronger emotional response than standard contextual ads.
- Mobile environments intensify attention and emotional resonance, which makes neuro-contextual alignment even more impactful on mobile devices.
- The strongest predictors of relevance come from Neuro-Contextual signals rather than identity-based data, supporting a more human and privacy-safe approach to advertising.
A New Perspective on Neuromarketing
Neuromarketing helps advertisers understand how people react to ads by measuring emotional response, attention, and cognitive load. The emotional state and motivation of the user are shaped by the content they choose to watch or read. These factors influence how open the brain is to the advertising that follows.
When an ad appears in an environment that matches their mindset, the brain responds more positively, processing becomes easier, emotional response increases, attention increases, and the ad feels more natural and less disruptive. This broadens the role of neuromarketing. Instead of evaluating only the creative, it now includes the context that surrounds it.
This shift also reflects the rise of AI in media planning. To capture real consumer behavior, neuromarketing must consider both the ad and the environment framing it. Neuro-Contextual Advertising brings these two elements together and creates a more human understanding of relevance.

How Neuro-Contextual Advertising Works
Neuro-Contextual Advertising aligns ads with the interest, emotion, and intent expressed by the surrounding content of an article or video. It reflects how the brain processes content in real time. This approach goes beyond traditional contextual advertising, which matches ads to topics or keywords. Instead, Neuro-Contextual Advertising takes into account emotional tone and intentions, which influence how open the brain is to receiving information.
People bring an emotional and motivational state into every moment of digital consumption. Some content evokes curiosity. Some build trust. Some sparks excitement. Some demand deeper cognitive effort. These states influence how receptive the brain is to new messages.
Our research shows that when ads align with these cues, the brain processes the message with less effort. Relevance becomes a function of the moment itself. AI supports this alignment by interpreting signals found directly in the content instead of relying on identity-based data. This protects privacy while supporting a more human understanding of attention and emotion. This is where the broader AI revolution is reshaping the planning phase for advertising.
Learn more about Neuro-Contextual
- How is Neuroscience Transforming the Digital Advertising Landscape
- Neuro-Contextual Advertising: Winning Audiences Through Interests, Emotions and Intentions
- Neuro-Contextual Advertising: From Industry Innovation to eMarketer’s Number One Trend
Deep dive into the Research
Three core signals were measured by using EEG brainwave technology: attention, emotional resonance, and neural engagement. Together, these indicators reveal how receptive and emotionally open people become when viewing different types of advertising.
Participants viewed non-contextual ads, standard IAB contextual ads, and neuro-contextual ads while their neural responses were analyzed. The results were clear:
Neuro-Contextual placements generated up to 3.5x higher neural engagement compared with non-contextual ads. This is meaningful because Cross-Brain Correlation is closely associated with memory formation and collective emotional processing.
The study also found a 26% stronger emotional response than standard contextual ads. This was shown through brain left side frontal activity linked to approach motivation. Signals related to trust, excitement, and approval appeared more strongly when the ad aligned with the emotional tone of the content.
Mobile environments amplified these effects. The research revealed that mobile consumption intensified both attention and emotional resonance, likely because mobile is a more personal and immersive setting. Across all indicators, the brain favored the moment that felt most coherent.
What Brands Can Learn From the Study
To build relevance, brands should consider how emotional tone, intention, and cognitive processing influence the moment in which an ad appears. When planning reflects these human signals, advertising becomes more intuitive and easier for the brain to receive.
AI systems that interpret interest, emotion, and intent without using personal data become valuable tools in this process. They help brands align with the mindset of the moment instead of the identity of the user. This reflects the brain’s natural processing style and supports a more privacy-safe understanding of relevance.
Liz, our proprietary neuro-contextual AI, interprets deeper signals of interest, emotion, and intent within content. This supports a more intuitive, privacy-first, and human-centered approach and reflects the promise of Artificial Intelligence Advertising for more human understanding.
If you want to explore the complete findings, including the full methodology and EEG framework, download the full research report here:



